Published Date: 2017-04-22 15:20:33
Subject: PRO/AH/EDR> Foot & mouth disease - Algeria (06): (SF) bov, st SAT1 NOT, st A, new strain, OIE
Archive Number: 20170422.4987489
FOOT AND MOUTH DISEASE - ALGERIA (06): (SETIF) BOVINE, SEROTYPE SAT1 NOT, SEROTYPE A, NEW STRAIN, OIE
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Date: Thu 20 Apr 2017
Source: OIE, WAHID (World Animal Health Information Database), weekly disease information 2017; 30(16) [edited]
Foot and mouth disease, Algeria
Information received on [and dated] 20 Apr 2017 from Dr Djamila Hadj Amar, Directrice des Services Vétérinaires, Services Vétérinaires, Ministère de l'Agriculture, du Développement Rural et de la Pêche, Alger, Algeria
Report type: Follow-up report No. 1
Date of start of the event: 7 Apr 2017
Date of confirmation of the event: 09 Apr 2017
Reason for notification: New strain of a listed disease in the country
Causal agent: Foot and mouth disease virus
Nature of diagnosis: Clinical, Laboratory (advanced)
This event pertains to a defined zone within the country
Outbreaks: There are no new outbreaks in this report
Source of the outbreak(s) or origin of infection: Unknown or inconclusive
Epidemiological comments: The OIE/FAO reference laboratory in Brescia (IZSLER) denied serotype SAT1 and confirmed serotype A.
Note from the World Animal Health Information and Analysis Department: from this date, the immediate notification published on 10 Apr 2017 will be rectified with serotype A.
Measures applied: movement control inside the country; disinfection / stamping out; official disposal of carcasses, by-products and waste; vaccination permitted (if a vaccine exists); no treatment of affected animals
Measures to be applied: no other measures
Diagnostic test results
Laboratory name and type / Species / Test / Test date / Result
Lombardy and Emilia Romagna Experimental Zooprophylactic Institute (IZSLER), Brescia (OIE Reference Laboratory) / Cattle / virus isolation / 13 Apr 2017 / Positive
The event is continuing. Weekly follow-up reports will be submitted.
[No new outbreaks of foot-and-mouth disease were officially registered during the past week, even though the local press is echoing a number of suspicions.
The Setif outbreak initially attributed to the SAT1 viral serotype has finally been confirmed as being due to serotype A by the FAO/OIE Reference Laboratory in Brescia, Italy. - Mod.AB
Subscribers are referred to the Algeria page of the WRLFMD, where the genotyping results of sequences from 5 FMDV-A strains identified in samples from 5 Algerian cattle have already been published. This relates to 3 samples collected on [24 Mar 2017] from cattle in Ouled Souid, Zemmoura, Relizane and 2 samples collected from cattle on [2 Apr 2017] in Boussena, Ouzna, Medea. The sequencing was applied by the FMD reference laboratory in Brescia, Italy. Their respective genotyping results are presented in tables showing their identity rate to the most closely related sequences from FMDV-A Africa G-IV strains (Algeria and Nigeria), as well as to 10 most closely related prototype sequences. The tables are available at http://www.wrlfmd.org/fmd_genotyping/2017/WRLMEG-2017-00028-Algeria-A-current-v2.pdf. A dendogram is included as well.
According to the data on WRLFMD genotyping pages (date of access [22 Apr 2017]), 3 additional samples from Algeria have been received at Pirbright on [18 Apr 2017]. The publication of their genotyping results is "pending". It may be assumed (but in need of confirmation) that these samples were collected in Setif.
Since 2011, virus strains of FMDV-A, topotype Africa, lineage G-IV have reportedly been reported from Sudan, Egypt, Nigeria, Cameroun and Ethiopia. According to vaccine matching tests carried out by the WRLFMD in 2016, a recent Egyptian FMDV-A field isolate (A/EGY/3/2016), belonging to the said genotype A/AFRICA/G-IV, obtained good matching results with the vaccine strain A/Eri 98 but not with A Iran 2005, ATUR 20/06 and A22IRQ. See 'Egypt" on page 15 of http://www.fao.org/fileadmin/user_upload/eufmd/docs/FMD_monthly_reports/2016/October_2016.pdf.
However the said results are not necessarily applicable to the recent Algerian FMDV-A Africa G-IV strain, and vaccine matching tests of the Algerian strain are urgently needed.
Hopefully, matching vaccines, in case indicated, will be found in vaccine-banks and/or be commercially available. This is essential for Algeria, as well as for its neighbors.
The use of heterogeneous vaccine strains, not capable to protect the naive animal population, in Algeria may negatively affect the vital trust and cooperation of animal owners during future vaccinations. So far, clinical FMD cases in Algeria have been reported only in cattle. The situation in small ruminants remains to be carefully checked. - Mod.AS
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