SAT 1 Information | Reference Laboratory for Foot-and-Mouth Disease

Foot-and-mouth disease virus serotype SAT 1 has recently been diagnosed in a variety of geographic locations outside of its traditional range of southern Africa.

The situation is rapidly evolving with new confirmed and suspected locations being discovered regularly.

Below are a links to a series of webpages with useful information regarding the SAT 1 situation and how to test for FMD serotype SAT 1.

Webpages and other websites

Lineage specific FMDV Real-time RT-PCR assays

Different real-time RT-PCR assays that have been designed to detect different Foot-and-mouth disease virus lineages in different parts of the world.

Each leaflet describes an assay for particular FMDV lineages expected to be circulating in a geographical location. A summary of all these real-time RT-PCR assays, including SAT 1 assays, can be found on this page.

Lineage specific FMDV Real-time RT-PCR assays

Phylogenetic tree of SAT 1 prototype strains

SAT 1 sequencing protocol

Method for the sequencing of SAT1 samples.

This is a two stage process. The first stage is to use RT-PCR to amplify the VP1-coding region of a SAT 1 positive sample. Two separate primer sets are described below to generate these products.

The second stage is to sequence the amplified RT-PCR products

SAT 1 sequencing protocol

WOAH Notice

Foot-and-mouth disease (FMD) continues to pose a serious and evolving threat to animal health, food security, livelihoods, and international trade. FMD (serotype SAT 1) has spread beyond its historical African range, causing outbreaks in countries previously free, including those in Southern Africa, Asia, Europe, and the Middle East. The dynamic nature of this epidemiological situation underscores the need for sustained global vigilance and adapted actions.

WOAH calls for action on foot-and-mouth disease (SAT1) international spread

WAHIS

WOAH's World Animal Health Information System (WAHIS) includes interactive mapping tools and dashboards to support data consultation, visualization and extraction of officially validated animal health data.

WAHIS

EMPRES-i+

FAO’s EMPRES Global Animal Disease Information System (EMPRES-i+) supports veterinary services by facilitating regional and global disease information sharing. EMPRES-i maps hundreds of thousands of records of animal diseases across 190 countries.

EMPRES-i+